Pulmonary haemorrhage, pulmonary infarction, and the lupus anticoagulant.

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Pulmonary haemorrhage, pulmonary infarction, and the lupus anticoagulant.

A patient with systemic lupus erythematosus developed pulmonary haemorrhage and pulmonary infarction as rare initial manifestations of her disease. The latter was associated with the presence of the circulating lupus anticoagulant. She recovered with pulse doses of methylprednisolone and plasmapheresis. Anticoagulants were not administered.

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A patient with a circulating lupus anticoagulant in the absence of systemic lupus erythematosus developed recurrent deep venous thromboses and pulmonary emboli. Pulmonary emboli recurred despite prolonged oral anticoagulant therapy and resulted in fatal pulmonary arterial hypertension. Extended anticoagulant therapy alone may not prevent recurrent thromboembolism in patients with a lupus antico...

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Pulmonary hemorrhage in pediatric lupus anticoagulant hypoprothrombinemia syndrome

Lupus anticoagulant-hypoprothrombinemia syndrome (LAHPS), a very rare disease that is caused by the presence of antifactor II antibodies, is usually counterbalanced by the prothrombotic effect of lupus anticoagulant (LAC). Patients with LAHPS are treated using fresh frozen plasma, steroids, immunosuppressive agents, and immunoglobulins for managing the disease and controlling hemorrhages. Notab...

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Pulmonary haemorrhage in the neonate

pulmonary haemorrhage (pH) in a sick neonate is a life-threatening complication and is often associated with a high mortality. it is now often seen in extreme preterm and very low birth weight infants who are growth restricted and have received surfactant with significant respiratory distress syndrome. the mainstay of treatment includes ventilation and vigorous resuscitation of a shocked and cr...

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ژورنال

عنوان ژورنال: Annals of the Rheumatic Diseases

سال: 1988

ISSN: 0003-4967

DOI: 10.1136/ard.47.10.869